Tris(1-adamantyl)phosphine is primarily utilized in the field of organic synthesis and catalysis. Its bulky structure makes it an effective ligand in transition metal-catalyzed reactions, particularly in cross-coupling reactions, where it enhances selectivity and efficiency. The compound is also employed in the development of advanced materials, such as polymers and coordination complexes, due to its ability to stabilize reactive intermediates. Additionally, it finds use in research focused on phosphine chemistry, where its unique steric properties are studied for designing novel catalysts and understanding reaction mechanisms.