2-(Dicyclohexylphosphino)biphenyl is a phosphine ligand utilized in transition metal-catalyzed cross-coupling reactions, including Suzuki-Miyaura, Heck, and Buchwald-Hartwig reactions. It improves catalyst stability, efficiency, and selectivity, promoting the formation of carbon-carbon and carbon-heteroatom bonds with high yields and purity. This enables the synthesis of complex organic molecules for pharmaceuticals, agrochemicals, and advanced materials. Its unique steric and electronic properties make it essential in fine chemical synthesis and industrial applications.