Widely used in cross-coupling reactions, particularly in Suzuki-Miyaura and Buchwald-Hartwig reactions, due to its strong electron-donating properties and steric bulk, which enhance catalytic activity and selectivity. It is a highly effective ligand for palladium-catalyzed processes, enabling the synthesis of complex organic molecules, including pharmaceuticals and agrochemicals. Its stability under reaction conditions and ability to facilitate challenging transformations make it valuable in industrial and academic research. Additionally, it is employed in the development of new catalytic systems for C-C and C-N bond formation, contributing to advancements in synthetic organic chemistry.