This chemical is primarily utilized as a ligand in transition metal-catalyzed reactions, particularly in cross-coupling processes such as Suzuki-Miyaura and Buchwald-Hartwig reactions. Its electron-rich and sterically hindered structure enhances the stability and reactivity of the metal complexes, enabling efficient catalytic cycles. It is especially valuable in synthesizing complex organic molecules, including pharmaceuticals and fine chemicals, where high selectivity and yield are critical. The trifluoromethyl groups contribute to the ligand's solubility in organic solvents, facilitating its use in homogeneous catalysis. Additionally, its unique steric and electronic properties make it suitable for challenging transformations that require precise control over reaction conditions.