Widely used as a ligand in transition metal catalysis, particularly in palladium-catalyzed cross-coupling reactions. It enhances the efficiency and selectivity of reactions such as Suzuki-Miyaura, Buchwald-Hartwig amination, and C-N bond formations. Its bulky structure helps stabilize reactive intermediates, enabling the synthesis of complex organic molecules, including pharmaceuticals and agrochemicals. Additionally, it is employed in the development of new catalytic processes for fine chemical production, offering improved yields and reduced byproducts. Its versatility makes it valuable in both academic research and industrial applications.