Chloro(Tert-Butyl)Phenylphosphine is primarily used in organic synthesis as a ligand in transition metal catalysis. It plays a significant role in facilitating various chemical reactions, including cross-coupling reactions, which are essential for creating complex organic molecules in pharmaceuticals and agrochemicals. Its steric and electronic properties make it effective in stabilizing metal complexes, enhancing reaction efficiency and selectivity. Additionally, it is employed in the development of advanced materials, such as polymers and catalysts, where precise control over molecular structure is crucial. Its applications also extend to research in coordination chemistry, aiding in the study of new catalytic processes and reaction mechanisms.