This chemical is widely used as a ligand in transition metal catalysis, particularly in cross-coupling reactions such as Suzuki-Miyaura and Buchwald-Hartwig couplings. Its sterically hindered and electron-rich structure enhances the stability and reactivity of metal complexes, making it valuable in synthesizing pharmaceuticals, agrochemicals, and fine chemicals. It is also employed in asymmetric catalysis to produce chiral compounds with high enantioselectivity. Additionally, its role in C-H activation and functionalization reactions has expanded its utility in organic synthesis, enabling the construction of complex molecular architectures efficiently.