1,1,1-Trifluoro-N-((11bS)-4-oxido-2,6-bis(4-(trifluoromethyl)phenyl)-8,9,10,11,12,13,14,15-octahydrodinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-yl)methanesulfonamide
98%
Reagent
Code: #244633
CAS Number
2757287-57-1
blur_circular Chemical Specifications
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Molecular Information
Weight
775.62 g/mol
Formula
C₃₅H₂₇F₉NO₅PS
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Storage & Handling
Storage
2-8°C, Sealed, Dry, Light-proof, Inert Gas
description Product Description
Used as a key chiral ligand in asymmetric catalysis, particularly in transition-metal-catalyzed reactions for the synthesis of enantiomerically pure pharmaceuticals. Its phosphorus center and rigid dinaphthyl backbone provide excellent stereocontrol, making it valuable in hydrogenation and cross-coupling reactions. Widely applied in the production of chiral intermediates for drugs targeting cardiovascular, neurological, and metabolic diseases. The trifluoromethyl groups enhance ligand stability and influence electronic properties, improving catalyst performance under industrial conditions.
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