(S)-2-(2-(Diphenylphosphanyl)phenyl)-4,5,5-triphenyl-4,5-dihydrooxazole
97%
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Widely used as a chiral ligand in asymmetric catalysis, this compound plays a key role in enantioselective transformations such as hydrogenation, cross-coupling, and C–H activation reactions. Its rigid oxazoline backbone and stereogenic center enable high enantioselectivity by effectively controlling the spatial environment around the metal center in catalytic systems. Particularly effective with rhodium, ruthenium, and palladium complexes, it facilitates the synthesis of optically active pharmaceuticals, agrochemicals, and fine chemicals. The diphenylphosphine group ensures strong coordination to transition metals, enhancing catalyst stability and activity under various reaction conditions. Its modular structure also allows for fine-tuning in catalyst design for specific industrial applications.
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