Used as a chiral ligand precursor in asymmetric synthesis, particularly in transition metal-catalyzed reactions. Its phosphine oxide group can be reduced to the corresponding phosphine, which coordinates with metals like palladium, rhodium, or ruthenium to form catalysts. These catalysts are effective in enantioselective transformations such as hydrogenations, allylic alkylations, and C–C bond-forming reactions. The (S)-configuration ensures stereochemical control, making it valuable in the synthesis of optically active pharmaceuticals and fine chemicals. The methoxymethyl ether group acts as a protecting group, enhancing stability and solubility during reaction sequences.