Used as a chiral ligand in asymmetric catalysis, particularly in transition-metal-catalyzed reactions such as hydrogenation and cross-coupling. Its rigid backbone and stereogenic centers enable high enantioselectivity in the synthesis of pharmaceutical intermediates and fine chemicals. Commonly employed in palladium- and rhodium-based catalytic systems to facilitate the formation of chiral centers with high optical purity. Valued in medicinal chemistry for enabling efficient, selective synthesis of bioactive molecules.