Used as a chiral ligand in asymmetric catalysis, particularly in transition metal-catalyzed reactions such as rhodium- or ruthenium-catalyzed asymmetric hydrogenation of prochiral olefins and ketones. Its rigid backbone and stereogenic centers enable high enantioselectivity in the synthesis of chiral intermediates for pharmaceuticals and fine chemicals. Commonly employed in the production of enantiomerically pure active pharmaceutical ingredients (APIs), especially in the development of beta-amino acids, amino alcohols, and other bioactive molecules. Also applied in palladium-catalyzed asymmetric cross-coupling reactions to construct chiral biaryl systems. Valued for its stability under reaction conditions and ability to induce high turnover and selectivity in industrial and academic research settings.