Widely used as a chiral ligand precursor in asymmetric catalysis, particularly in rhodium- and ruthenium-catalyzed enantioselective hydrogenation reactions. It plays a key role in the synthesis of chiral amines, amino acids, and other pharmaceutical intermediates by enabling high enantioselectivity and yield. Commonly employed in the production of active pharmaceutical ingredients (APIs) where stereochemical purity is critical. Its robust performance under various reaction conditions makes it valuable in both academic research and industrial-scale drug manufacturing.