((2S,3S)-4-(anthracen-9-yl)-3-(tert-butyl)-2,3-dihydrobenzo[d][1,3]oxaphosphol-2-yl)di-tert-butylphosphine oxide
97%, 99% ee
Reagent
Code: #236686
CAS Number
2374143-29-8
blur_circular Chemical Specifications
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Molecular Information
Weight
530.63 g/mol
Formula
C₃₃H₄₀O₂P₂
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Storage & Handling
Storage
2-8°C, dry
description Product Description
Used as a chiral ligand in asymmetric catalysis, particularly in transition-metal-catalyzed reactions such as asymmetric hydrogenation and cross-coupling reactions. Its rigid anthracenyl backbone and stereogenic centers enhance enantioselectivity, making it valuable in the synthesis of optically active pharmaceuticals and fine chemicals. The phosphine oxide group can be reduced to the corresponding phosphine, enabling its use in palladium- or rhodium-based catalytic systems. Its steric bulk from tert-butyl groups helps control metal coordination geometry, improving reaction selectivity.
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