[S(R)]-N-[(1R)-1-[5-(Diphenylphosphino)-9,9-dimethyl-9H-xanthen-4-yl]-2,2-dimethylpropyl]-2-methyl-2-propanesulfinamide
95%
science Other reagents with same CAS 2162939-92-4
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Widely used as a chiral ligand precursor in asymmetric catalysis, this compound plays a key role in the synthesis of enantiomerically enriched molecules. It is particularly effective in palladium-catalyzed asymmetric allylic alkylation reactions, where it helps achieve high enantioselectivity. The rigid xanthene backbone and tunable phosphine group enhance metal coordination and stereocontrol. Due to its steric bulk and well-defined chiral environment, it enables efficient asymmetric induction in the formation of carbon–carbon and carbon–heteroatom bonds. It is commonly employed in pharmaceutical and fine chemical synthesis where precise stereochemistry is critical.
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