[S(R)]-N-[(1R)-1-[5-(Diphenylphosphino)-9,9-dimethyl-9H-xanthen-4-yl]-2,2-dimethylpropyl]-2-methyl-2-propanesulfinamide
95%
Reagent
Code: #236680
CAS Number
2162939-92-4
blur_circular Chemical Specifications
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Molecular Information
Weight
583.76 g/mol
Formula
C₃₆H₄₂NO₂PS
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Registry Numbers
MDL Number
MFCD32697193
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Storage & Handling
Storage
Room temperature, argon
description Product Description
Widely used as a chiral ligand precursor in asymmetric catalysis, this compound plays a key role in the synthesis of enantiomerically enriched molecules. It is particularly effective in palladium-catalyzed asymmetric allylic alkylation reactions, where it helps achieve high enantioselectivity. The rigid xanthene backbone and tunable phosphine group enhance metal coordination and stereocontrol. Due to its steric bulk and well-defined chiral environment, it enables efficient asymmetric induction in the formation of carbon–carbon and carbon–heteroatom bonds. It is commonly employed in pharmaceutical and fine chemical synthesis where precise stereochemistry is critical.
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