Used as a ligand in palladium-catalyzed cross-coupling reactions, particularly in Suzuki-Miyaura and Buchwald-Hartwig aminations. Its rigid, chiral structure enhances enantioselectivity and catalytic efficiency in asymmetric synthesis. Commonly applied in pharmaceutical manufacturing for constructing carbon-heteroatom and carbon-carbon bonds under mild conditions. Exhibits high thermal stability and electron-donating properties, making it suitable for challenging transformations involving sterically hindered substrates.