Used as a chiral ligand in asymmetric catalysis, particularly in transition-metal-catalyzed reactions. It plays a key role in enantioselective transformations such as hydrogenation and cross-coupling reactions, where high stereocontrol is required. Its structure enables strong coordination to metals like ruthenium, rhodium, or iridium, enhancing catalytic activity and selectivity. Commonly applied in pharmaceutical synthesis for producing single-enantiomer compounds. The presence of trifluoromethyl groups improves ligand stability and influences electronic properties, making it effective in challenging catalytic environments.