[S(R)]-N-[(S)-[2-(Di-tert-butylphosphino)phenyl[(2-naphthalenyl)methyl]-2-methyl-2-propanesulfinamide
≥95%
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Widely used as a chiral ligand in asymmetric catalysis, this compound plays a key role in enantioselective transformations, particularly in palladium-catalyzed allylic substitution and cross-coupling reactions. Its steric bulk and well-defined chiral environment enable high enantioselectivity in the synthesis of complex organic molecules, making it valuable in pharmaceutical and fine chemical industries. The tert-butyl and naphthyl groups enhance ligand stability and influence metal coordination geometry, leading to improved catalytic efficiency and stereocontrol. It is especially effective in reactions requiring precise spatial arrangement around the metal center for optimal asymmetric induction.
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