[S(R)]-N-[(1S)-1-[2-(Dicyclohexylphosphanyl)phenyl]-2,2-dimethylpropyl]-2-methyl-2-propanesulfinamide
≥95%
Reagent
Code: #236108
CAS Number
2565792-30-3
science Other reagents with same CAS 2565792-30-3
blur_circular Chemical Specifications
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Molecular Information
Weight
463.70 g/mol
Formula
C₂₇H₄₆NOPS
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Storage & Handling
Storage
2-8°C, avoid light, inert gas storage
description Product Description
Widely used as a chiral ligand precursor in asymmetric catalysis, this compound plays a key role in the synthesis of enantiomerically pure pharmaceuticals and fine chemicals. Its primary application lies in transition metal-catalyzed asymmetric reactions, especially in the development of palladium- and rhodium-based catalysts for C–C bond formation, such as asymmetric hydrogenation and cross-coupling reactions. The sulfinamide and phosphine groups work in tandem to stabilize metal centers while providing high stereocontrol. Due to its rigid backbone and well-defined chiral environment, it delivers excellent enantioselectivity in complex molecular settings, making it valuable in academic research and industrial drug synthesis. It is also employed in the preparation of other chiral auxiliaries and ligands for specialized catalytic transformations.
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