[S(R)]-N-[(S)-[3,5-Di-tert-butyl-4-methoxyphenyl][5-(diphenylphosphino)-9,9-dimethyl-9H-xanthen-4-yl]methyl]-2-methyl-2-propanesulfinamide
≥95%
Reagent
Code: #236106
CAS Number
2565792-28-9
blur_circular Chemical Specifications
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Molecular Information
Weight
746.00 g/mol
Formula
C₄₇H₅₆NO₃PS
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Storage & Handling
Storage
2-8°C, avoid light, inert gas storage
description Product Description
Widely used as a chiral ligand precursor in asymmetric catalysis, this compound plays a key role in enantioselective transformations, particularly in the synthesis of pharmaceuticals and fine chemicals. Its structure enables high stereocontrol in metal-catalyzed reactions such as asymmetric hydrogenation and cross-coupling reactions. The sulfonamide group acts as a directing and stabilizing moiety, while the phosphine center coordinates effectively with transition metals like palladium, rhodium, and ruthenium. Due to its bulky tert-butyl and xanthene groups, it provides excellent steric and electronic tuning, resulting in high enantioselectivity and catalyst efficiency. It is especially valuable in the development of chiral catalysts for industrial-scale processes where precise stereochemistry is critical.
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