Widely used as a chiral ligand in asymmetric catalysis, this compound plays a key role in enantioselective transformations such as hydrogenation, cross-coupling, and C–H activation reactions. Its sterically hindered, electron-rich phosphine groups enhance metal coordination and promote high enantioselectivity when paired with transition metals like palladium, rhodium, or ruthenium. It is particularly effective in reactions requiring precise stereochemical control, making it valuable in the synthesis of pharmaceutical intermediates and fine chemicals where a specific enantiomer is required. The compound’s robust biphenyl backbone and tunable methoxy and chloro substituents allow for fine-tuning of catalytic activity and selectivity across different reaction systems.