(S)-(-)-2,2',6,6'-Tetramethoxy-4,4'-bis[di(3,5-xylyl)phosphino]-3,3'-bipyridine
97%
Reagent
Code: #234613
CAS Number
443347-10-2
blur_circular Chemical Specifications
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Molecular Information
Weight
756.85 g/mol
Formula
C₄₆H₅₀N₂O₄P₂
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Registry Numbers
MDL Number
MFCD04974235
thermostat
Physical Properties
Melting Point
158-162°C
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Storage & Handling
Storage
Room temperature
description Product Description
Widely used as a chiral ligand in asymmetric catalysis, this compound plays a key role in enantioselective transformations, particularly in transition metal-catalyzed reactions. It is highly effective in palladium- and rhodium-catalyzed asymmetric cross-coupling and hydrogenation reactions, where it helps induce high enantiomeric excess. Its sterically bulky and electron-rich phosphine groups enhance metal coordination and stabilize catalytic intermediates, improving both reactivity and selectivity. Due to its rigid bipyridine backbone and tailored substituents, it is especially valuable in synthesizing chiral pharmaceuticals and fine chemicals where precise stereocontrol is required.
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