(S)-(-)-2,2',6,6'-Tetramethoxy-4,4'-bis[di(3,5-xylyl)phosphino]-3,3'-bipyridine
97%
science Other reagents with same CAS 443347-10-2
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Widely used as a chiral ligand in asymmetric catalysis, this compound plays a key role in enantioselective transformations, particularly in transition metal-catalyzed reactions. It is highly effective in palladium- and rhodium-catalyzed asymmetric cross-coupling and hydrogenation reactions, where it helps induce high enantiomeric excess. Its sterically bulky and electron-rich phosphine groups enhance metal coordination and stabilize catalytic intermediates, improving both reactivity and selectivity. Due to its rigid bipyridine backbone and tailored substituents, it is especially valuable in synthesizing chiral pharmaceuticals and fine chemicals where precise stereocontrol is required.
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