(1S,2S)-2-(Diphenylphosphino)cyclohexylamine
97%
Reagent
Code: #234559
CAS Number
452304-63-1
blur_circular Chemical Specifications
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Molecular Information
Weight
283.35 g/mol
Formula
C₁₈H₂₂NP
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Registry Numbers
MDL Number
MFCD16876055
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Storage & Handling
Storage
Room temperature, light-proof, inert gas
description Product Description
Widely used as a chiral ligand in asymmetric catalysis, this compound plays a key role in enantioselective hydrogenation reactions. It is particularly effective in the synthesis of chiral amines and amino acids, which are important intermediates in pharmaceutical manufacturing. Its rigid cyclohexyl backbone and well-defined stereochemistry enhance selectivity and catalytic efficiency when coordinated to transition metals like rhodium or ruthenium. It is also employed in the development of catalysts for industrial-scale processes where high enantiomeric excess is required. Due to its ability to induce asymmetry, it supports the production of single-enantiomer drugs, improving their efficacy and reducing side effects.
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