(S)-4-Benzyl-2-((S)-1-(diphenylphosphanyl)piperidin-2-yl)-4,5-dihydrooxazole
97%
Reagent
Code: #233569
CAS Number
2757084-47-0
blur_circular Chemical Specifications
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Molecular Information
Weight
428.51 g/mol
Formula
C₂₇H₂₉N₂OP
thermostat
Physical Properties
Boiling Point
563.8±60.0 °C(Predicted)
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Storage & Handling
Storage
2-8°C, light-proof, inert gas
description Product Description
Used as a chiral ligand in asymmetric catalysis, particularly in transition metal-catalyzed reactions such as hydrogenation and cross-coupling. Its phosphine and oxazoline groups coordinate effectively with metals like palladium, rhodium, and ruthenium, enabling high enantioselectivity in the synthesis of pharmaceutical intermediates and fine chemicals. Commonly applied in the production of optically active compounds where stereochemistry is critical, including active pharmaceutical ingredients (APIs). The rigid structure and defined chirality enhance reaction selectivity and yield under mild conditions.
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