(4S,5R)-2-((R)-1-(Diphenylphosphanyl)piperidin-2-yl)-4,5-diphenyl-4,5-dihydrooxazole
97%
Reagent
Code: #233564
CAS Number
2757084-61-8
blur_circular Chemical Specifications
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Molecular Information
Weight
490.58 g/mol
Formula
C₃₂H₃₁N₂OP
thermostat
Physical Properties
Boiling Point
622.1±65.0 °C(Predicted)
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Storage & Handling
Storage
2-8°C, light-proof, inert gas
description Product Description
Widely used as a chiral ligand in asymmetric catalysis, this compound plays a key role in enantioselective hydrogenation reactions. It is particularly effective in the reduction of prochiral olefins and ketones, enabling the synthesis of optically active compounds with high enantiomeric excess. Its application is prominent in pharmaceutical manufacturing, where precise stereochemistry is crucial for drug efficacy and safety. The ligand's rigid structure and well-defined chiral environment enhance selectivity and catalytic efficiency when coordinated with transition metals such as iridium or rhodium. It is also employed in the development of fine chemicals and agrochemicals requiring enantiopure intermediates.
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