(S)-2-((R)-1-(Diphenylphosphanyl)piperidin-2-yl)-4-isopropyl-4,5-dihydrooxazole
97%
Reagent
Code: #233560
CAS Number
2757084-56-1
blur_circular Chemical Specifications
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Molecular Information
Weight
380.46 g/mol
Formula
C₂₃H₂₉N₂OP
thermostat
Physical Properties
Boiling Point
496.1±55.0 °C(Predicted)
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Storage & Handling
Storage
2-8°C, light-proof, inert gas
description Product Description
Widely used as a chiral ligand in asymmetric catalysis, this compound plays a key role in enantioselective hydrogenation reactions. It is particularly effective in the synthesis of chiral amines and amino acid derivatives, which are important building blocks in pharmaceuticals. Due to its rigid oxazoline and phosphine groups, it forms stable complexes with transition metals like rhodium and iridium, enhancing catalytic activity and stereocontrol. Its application is prominent in the production of active pharmaceutical ingredients (APIs) where high enantiomeric purity is required. The ligand’s ability to induce high enantioselectivity makes it valuable in industrial-scale processes for drugs and fine chemicals.
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