(4S,5R)-2-((S)-1-(Diphenylphosphanyl)piperidin-2-yl)-4,5-diphenyl-4,5-dihydrooxazole
97%
Reagent
Code: #233269
CAS Number
2757084-49-2
blur_circular Chemical Specifications
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Molecular Information
Weight
490.58 g/mol
Formula
C₃₂H₃₁N₂OP
thermostat
Physical Properties
Boiling Point
622.1±65.0 °C(Predicted)
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Storage & Handling
Storage
2-8°C, light-proof, inert gas
description Product Description
Used as a chiral ligand in asymmetric catalysis, particularly in transition-metal-catalyzed reactions such as asymmetric hydrogenation and cross-coupling reactions. Its rigid oxazoline backbone and stereogenic centers enable high enantioselectivity, making it valuable in the synthesis of chiral pharmaceuticals and fine chemicals. The diphenylphosphine group facilitates strong coordination to metals like rhodium, ruthenium, and palladium, enhancing catalytic activity and stereocontrol. Commonly employed in academic and industrial research for developing enantiopure compounds.
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