(R)-(2,3-Dimethyl-3-((Triethylsilyl)Oxy)Butyl)Diphenylphosphine Oxide
97%
science Other reagents with same CAS 1227926-70-6
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description Product Description
Used as a chiral ligand precursor in asymmetric catalysis, particularly in transition-metal-catalyzed reactions where high enantioselectivity is required. Its silyl-protected hydroxyl group allows for selective deprotection and further functionalization, enabling modular synthesis of complex molecules. Commonly applied in the development of pharmaceutical intermediates and fine chemicals, especially in routes requiring stereochemical control. The phosphine oxide moiety can be reduced to the corresponding phosphine, making it valuable in the preparation of chiral phosphine ligands for catalytic asymmetric transformations such as hydrogenation and cross-coupling reactions.
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