(R)-N-((R)-(2-(Di-tert-butylphosphino)phenyl)(phenyl)methyl)-N,2-dimethylpropane-2-sulfinamide
95%
Reagent
Code: #231402
CAS Number
2757083-12-6
blur_circular Chemical Specifications
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Molecular Information
Weight
445.64 g/mol
Formula
C₂₆H₄₀NOPS
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Storage & Handling
Storage
2-8°C, light-proof, inert gas
description Product Description
Widely used as a chiral ligand in asymmetric catalysis, this compound plays a key role in enantioselective transformations, particularly in transition-metal-catalyzed reactions. It is highly effective in palladium-catalyzed asymmetric allylic alkylation and other cross-coupling reactions where control of stereochemistry is critical. The bulky tert-butyl groups and the rigid backbone enhance stereoselectivity by creating a well-defined chiral environment around the metal center. Its sulfinamide moiety allows for easy handling and purification, making it a practical choice in synthetic organic chemistry. It is often employed in the synthesis of pharmaceuticals and fine chemicals where high enantiomeric excess is required.
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