(R)-2-(2-Chloro-6-(diphenylphosphaneyl)phenyl)-4-isopropyl-4,5-dihydrooxazole
97%
Reagent
Code: #231384
CAS Number
2757082-52-1
blur_circular Chemical Specifications
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Molecular Information
Weight
407.8723 g/mol
Formula
C₂₄H₂₃ClNOP
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Storage & Handling
Storage
2-8°C, light-proof, inert gas
description Product Description
Used as a chiral ligand in asymmetric catalysis, particularly in transition metal-catalyzed reactions such as asymmetric hydrogenation and cross-coupling reactions. Its phosphine-oxazoline structure provides excellent stereocontrol, making it valuable in the synthesis of enantiomerically pure pharmaceuticals and fine chemicals. The ligand coordinates effectively with metals like palladium, rhodium, and iridium, enhancing catalytic activity and enantioselectivity. Commonly applied in the preparation of chiral intermediates for drugs and biologically active compounds.
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