(R)-4-(tert-Butyl)-2-(2-chloro-6-(diphenylphosphaneyl)phenyl)-4,5-dihydrooxazole
97%
Reagent
Code: #231383
CAS Number
2757082-51-0
blur_circular Chemical Specifications
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Molecular Information
Weight
421.8989 g/mol
Formula
C₂₅H₂₅ClNOP
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Storage & Handling
Storage
2-8°C, light-proof, inert gas
description Product Description
Used as a chiral ligand in asymmetric catalysis, particularly in transition metal-catalyzed reactions such as rhodium- or ruthenium-mediated enantioselective hydrogenations. Its phosphine-oxazoline structure provides excellent stereocontrol, making it valuable in the synthesis of optically active pharmaceuticals and fine chemicals. The bulky tert-butyl and diphenylphosphine groups enhance steric and electronic tuning, improving catalyst selectivity and activity. Commonly employed in the production of chiral intermediates for drugs and agrochemicals where high enantiomeric excess is required.
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