(R)-(2'-Isopropoxy-[1,1'-binaphthalen]-2-yl)diphenylphosphine
98%
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Widely used as a chiral ligand in asymmetric catalysis, this compound plays a key role in enantioselective transformations such as hydrogenation, cross-coupling, and C–H activation reactions. Its sterically bulky and electronically tunable structure enhances selectivity and reactivity when coordinated to transition metals like rhodium, ruthenium, or palladium. It is particularly effective in reactions requiring high enantiomeric excess, making it valuable in the synthesis of pharmaceutical intermediates and fine chemicals. The binaphthyl backbone provides axial chirality essential for asymmetric induction, while the isopropoxy and diphenylphosphine groups fine-tune the ligand’s coordination environment. Its application enables efficient construction of chiral centers in complex organic molecules.
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