(R)-2-((S)-1-(Diphenylphosphanyl)piperidin-2-yl)-4-isopropyl-4,5-dihydrooxazole
97%
Reagent
Code: #229511
CAS Number
2757084-50-5
blur_circular Chemical Specifications
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Molecular Information
Weight
380.46 g/mol
Formula
C₂₃H₂₉N₂OP
thermostat
Physical Properties
Boiling Point
496.1±55.0 °C(Predicted)
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Storage & Handling
Storage
2-8°C, light-proof, inert gas
description Product Description
Widely used as a chiral ligand in asymmetric catalysis, particularly in transition metal-catalyzed reactions. It plays a key role in enantioselective hydrogenation and cross-coupling reactions, where high stereocontrol is required. Its rigid oxazoline and phosphine groups coordinate effectively with metals like rhodium, ruthenium, and palladium, enhancing catalytic activity and selectivity. Commonly applied in the synthesis of pharmaceutical intermediates and fine chemicals where specific enantiomers must be obtained. The ligand’s stereochemistry enables precise control over product chirality, making it valuable in industrial and academic research settings.
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