Used as a chiral ligand in asymmetric catalysis, particularly in enantioselective hydrogenation reactions. Its rigid, C2-symmetric structure enables high stereocontrol, making it valuable in the synthesis of chiral pharmaceuticals and fine chemicals. The electron-withdrawing trifluoromethyl groups enhance ligand stability and influence metal center reactivity. Commonly employed with rhodium or ruthenium complexes, it facilitates the production of single-enantiomer products in high yield and ee.