Used as a chiral ligand in asymmetric catalysis, particularly in transition-metal-catalyzed reactions such as asymmetric hydrogenation and cross-coupling reactions. Its rigid backbone and stereogenic centers enable high enantioselectivity, making it valuable in the synthesis of optically active pharmaceuticals and fine chemicals. The phosphine oxide group can be reduced to the corresponding phosphine, which coordinates effectively with metals like palladium, rhodium, and ruthenium to form active catalytic species. Its steric bulk and electronic properties enhance catalyst stability and selectivity under various reaction conditions.