Used as a key ligand in transition metal catalysis, particularly in palladium-catalyzed cross-coupling reactions. Its phosphine oxide group provides strong electron-withdrawing properties, enhancing catalyst stability and reactivity. Commonly employed in Suzuki, Heck, and Buchwald–Hartwig aminations for forming carbon-carbon and carbon-nitrogen bonds in pharmaceutical and agrochemical synthesis. Also utilized in the development of phosphorescent materials and as a building block in designing functional ligands for asymmetric catalysis.