Used as a ligand in palladium-catalyzed cross-coupling reactions, particularly in Suzuki-Miyaura and Buchwald-Hartwig aminations. Its bulky di-tert-butylphosphine group enhances electron density on the metal center, improving catalytic activity and stability. The N-phenylpyrrole moiety contributes to solubility and can influence the steric environment around the metal, enabling selective transformations. Commonly applied in the synthesis of pharmaceuticals, agrochemicals, and functional materials where efficient C–C and C–N bond formation is required.