Widely used as a ligand in transition metal-catalyzed cross-coupling reactions, particularly in palladium-catalyzed processes such as Suzuki-Miyaura and Buchwald-Hartwig aminations. Its steric bulk and electron-rich nature enhance catalytic activity and improve selectivity, especially in the formation of carbon-carbon and carbon-nitrogen bonds. Commonly employed in the synthesis of pharmaceuticals, agrochemicals, and organic materials where high catalyst efficiency and stability are required. Also valued in industrial-scale reactions due to its robust performance under various reaction conditions.