Used as a bulky monodentate phosphine ligand in palladium-catalyzed cross-coupling reactions, particularly in the synthesis of biaryl compounds. Its steric bulk and electron-rich nature enhance catalytic activity and improve selectivity in challenging transformations such as Suzuki-Miyaura and Buchwald-Hartwig aminations. The isopropoxy and isopropyl substituents contribute to increased solubility and stability of the catalyst complex, allowing reactions to proceed efficiently under mild conditions. Commonly employed in pharmaceutical and agrochemical synthesis where high yields and functional group tolerance are required.