Widely used as a ligand in palladium-catalyzed cross-coupling reactions, this compound plays a key role in forming carbon-carbon and carbon-heteroatom bonds. Its steric and electronic properties make it especially effective in Suzuki-Miyaura and Buchwald-Hartwig amination reactions, where it helps achieve high yields and selectivity under mild conditions. The ligand is valued for promoting catalytic activity with low catalyst loadings, even in the coupling of sterically hindered or electron-rich substrates. It is commonly employed in the synthesis of pharmaceuticals, agrochemicals, and organic materials where precise bond formation is critical.