Widely used as a ligand in palladium-catalyzed cross-coupling reactions, this compound enhances catalytic efficiency and stability. It is particularly effective in Suzuki-Miyaura and Buchwald-Hartwig aminations, where it enables coupling under mild conditions with high yields. Its steric bulk and electron-rich phosphine group facilitate oxidative addition and prevent catalyst deactivation. Commonly employed in pharmaceutical synthesis and materials science, it supports the formation of carbon-carbon and carbon-heteroatom bonds in complex molecules.