Used as a ligand in palladium-catalyzed cross-coupling reactions, enabling efficient carbon-carbon bond formation in organic synthesis. Its bulky structure enhances catalytic activity and selectivity, particularly in Suzuki, Negishi, and Buchwald-Hartwig amination reactions. Valued in pharmaceutical and agrochemical industries for constructing complex molecules. Also employed in the development of advanced materials and transition-metal catalysts due to its strong electron-donating properties and stability.