Di(1-adamantyl)-n-butylphosphine
80%
Reagent
Code: #168141
Alias
n-butylbis(1-adamantyl)phosphine
CAS Number
321921-71-5
blur_circular Chemical Specifications
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Molecular Information
Weight
358.54 g/mol
Formula
C₂₄H₃₉P
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Registry Numbers
MDL Number
MFCD05861606
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Storage & Handling
Storage
2-8°C, light-proof, inert gas
description Product Description
Used as a highly sterically hindered phosphine ligand in transition metal catalysis, particularly in cross-coupling reactions such as Suzuki-Miyaura and Buchwald-Hartwig aminations. Its rigid adamantyl groups enhance catalyst stability and promote reductive elimination, improving reaction efficiency and selectivity. Effective in palladium-catalyzed C–N and C–C bond formations where conventional ligands may fail. Also applied in the synthesis of pharmaceuticals and functional materials requiring mild reaction conditions and high functional group tolerance.
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