Used as a ligand in transition metal catalysis, particularly in palladium-catalyzed cross-coupling reactions. Its electron-donating properties and steric profile enhance catalytic efficiency and stability of metal complexes. Commonly applied in Suzuki–Miyaura and Buchwald–Hartwig aminations for forming carbon–carbon and carbon–nitrogen bonds in pharmaceutical and agrochemical synthesis. The methoxy substituents improve solubility and coordination behavior, making it suitable for reactions under mild conditions. Also employed in the development of homogeneous catalysts where selective and efficient transformations are required.