Used as a ligand in transition metal-catalyzed coupling reactions, particularly in palladium-catalyzed cross-coupling processes such as Suzuki-Miyaura and Buchwald-Hartwig aminations. Its electron-deficient aryl groups enhance catalyst stability and reactivity, especially in reactions requiring high selectivity or involving sterically hindered substrates. Also employed in the synthesis of phosphine-based catalysts for homogeneous catalysis, where the bromo substituents allow further functionalization via post-synthetic modifications.