Widely used as a bulky, electron-rich phosphine ligand in palladium-catalyzed cross-coupling reactions. It enhances catalytic activity and stability, especially in challenging transformations involving sterically hindered substrates. Commonly applied in Suzuki–Miyaura and Buchwald–Hartwig aminations, where it enables efficient carbon–carbon and carbon–heteroatom bond formation under mild conditions. Its rigid adamantyl groups contribute to high thermal stability and improved selectivity. Frequently chosen for synthesizing complex organic molecules, including pharmaceuticals and functional materials, due to its reliable performance in low catalyst loadings.