Used extensively in the formulation of lipid nanoparticles (LNPs) for drug delivery, particularly in mRNA-based therapeutics. Its PEGylated structure enhances nanoparticle stability by reducing aggregation and prolonging circulation time in the bloodstream. The polyethylene glycol (PEG) chain shields the lipid surface from immune recognition, decreasing clearance by the reticuloendothelial system. This compound also helps control particle size during LNP assembly and improves targeting efficiency to specific tissues. It is a key component in advanced delivery systems for vaccines and cancer therapies.