Used extensively in the development of lipid-based drug delivery systems, particularly in liposomal formulations and lipid nanoparticles (LNPs). Its primary application lies in enhancing the stability and fusogenic properties of liposomes, making it valuable in gene delivery and vaccine platforms. The molecule contributes to membrane fusion and endosomal escape, which improves intracellular delivery of nucleic acids such as mRNA and siRNA. It is especially useful in targeted therapies where efficient cellular uptake is critical. Due to its functionalized headgroup, it also serves as a linker for conjugating targeting ligands or imaging agents in diagnostic and therapeutic applications.