Sevelamer HCl is primarily used in the management of hyperphosphatemia in patients with chronic kidney disease (CKD) who are on dialysis. It works by binding to phosphate in the gastrointestinal tract, preventing its absorption into the bloodstream. This helps to lower and control serum phosphate levels, which is crucial in CKD patients as elevated phosphate can lead to complications such as bone disorders and cardiovascular issues. Additionally, Sevelamer HCl may also help in reducing serum cholesterol levels, providing an added benefit for patients with lipid abnormalities. It is typically administered orally in the form of tablets or powder, making it convenient for long-term use in managing chronic conditions.