Used in research to inhibit SHP-1 and SHP-2 phosphatases, NSC87877 helps study signaling pathways in immune cells and cancer. It has shown potential in enhancing T-cell activation, making it valuable in immunology and oncology studies. Researchers also use it to explore insulin signaling and diabetes-related mechanisms due to its effect on insulin receptor regulation. Its role in modulating cell growth and apoptosis supports investigation into new cancer therapies.